Cutting edge imaging in perinatal care, for better diagnosis and treatment of perinatal conditions.

 Created by the PremUp foundation in 2008 and co-financed by the Ile de France region, Premimage® is a platform for experimental research in perinatal imaging (ultrasound and MRI) which is unique in France. It is based on two teams belonging to INRA (the National Institute for Research in Agronomics) who provide animal models, an industrial partner for the latest generation in medical imaging and teams of researchers and clinicians from the PremUp network.

The aim of Premimage® is the evaluation of new diagnostic tools for high-risk pregnancies and cerebral and pulmonary lesions in premature babies.

The Premimage® organisation uses the most innovative imaging techniques - in ultrasound and highly sensitive quantitative elastography - in the field of perinatal care, in order to detect any conditions that may affect the mother and child as early as possible and to treat them better. Premimage brings together specialists in imaging in gynaecology, obstetrics and neonatalogy and in paediatric radiology. Three elastographs have been acquired by the PremUp Foundation PremUp in order to study the toughness of certain maternal and neonatal tissues in a non-invasive way. These purchases have been made possible by support from the Ile-de-France area and an industrial partnership with the manufacturer of these ultra-sophisticated devices, Supersonic.

Scientific Project Leaders

  • Pr Vassilis Tsatsaris, PUPH (University Professor and Hospital Practitioner), Gynaecologist/Obstetrician
  • Pr Catherine Adamsbaum, PUPH, Paediatric Radiologist, Paris Descartes.
  • Pr Guy Sebag, PU-PH, Paediatric Radiologist, Paris-Diderot.


The early detection of cerebral lesions in premature babies at a stage which is potentially reversible thanks to a twofold experimental approach:

  • The use of magnetic resonance micro imaging to detect cerebral lesions in small animals.
  • The performance of very early brain MRIs in premature babies. Thanks to anti-magnetic incubators it is now possible to perform MRIs in the first hours of life particularly in very premature babies under artificial respiration.

 Use emerging medical imaging techniques, and adapt them if necessary for:

  • Identifying cells responsible for cerebral lesions in order to facilitate the implementation of therapeutics.
  • Quantifying the cerebral vascularisation of premature infants using 3D Doppler ultrasound and validating this tool as a prognostic factor for neurological lesions.